Personalized therapy in craniopharyngioma—novel perspectives and limitations

Craniopharyngiomas are embryonic, histologically benign malformations of the sellar/parasellar region. Despite high survival rates (87% to 95% 20-yr overall survival in childhood-onset craniopharyngioma), quality of life is impaired in most long-term survivors due to sequelae caused by the anatomical proximity of the tumor to optic structures and hypothalamic–pituitary axes.